Thursday, 16th December 2004, 4:00 pm

Mathematics Building, Lecture Hall 2

Professor Boaz Nadler

(Yale University)

"Mathematical Models for ionic permeation through open protein channels"

** Abstract: **
Protein channels are macromolecules with holes down their middle that span
the membranes of biological cells. They control almost all ionic flow into
and out of cells and thus govern an enormous range of physiological function
important in health and disease.

In this talk I'll review the basic experimental knowledge on ion flow through these proteins and describe mathematical modelling approaches that aim to explain and predict the (biological) function of these channels given their structure. Interesting connections to the theory of stochastic processes and to non-equilibrium statistical mechanics will be described as well as some theoretical open questions.

Light refreshments will be served in the faculty lounge at 3:30.

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